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. 2016 May 3;24:12. doi: 10.1186/s40199-016-0152-y

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© Ziaei et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Spontaneous locomotor activity was measured in open field test. Total distance moved of rats in each group was checked. Data were collected over 6 consecutive days (1, 3, 7, 10, 14, 21 after injection of MIA) and averaged per group (n = 6). Topical administration of the formulation in group (T) significantly increased the total distance moved after 7 days and in group (P) after 3 days. Data present as mean ± SEM; *p < 0.05, **p < 0.01, ***p < 0.001 compared to group (N)