Table 4.
Differentially methylated CGIs in promoter, intragenic and intergenic regions
| CGIs | # | % | Differentially methylated | % | Brain hypermethylated | Brain hypomethylated | Associated genes |
|---|---|---|---|---|---|---|---|
| Total | 33054 | 100.0 | 6877 | 20.8 | 4622 | 2255 | 3652 |
| Promoter | 9985 | 30.2 | 1186 | 11.9 | 748 | 438 | 1357 |
| Intragenic | 8954 | 27.1 | 2055 | 23.0 | 1246 | 809 | 2295 |
| Intergenic | 14820 | 44.8 | 3743 | 25.3 | 2677 | 1066 | 0 |
We calculated the relative methylation levels for CGIs with at least three CpG sites, and determined differentially methylated CGIs using Fisher’s exact test. Table shows the number of differentially methylated CGIs and associated genes in blood and brain