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. 2016 Apr 7;1(4):e83116. doi: 10.1172/jci.insight.83116

Figure 2. Vaccinia vaccine immunotherapy abrogates fibrocyte recruitment and lung collagen deposition.

Figure 2

(A) ELISA of blood serum CXCL12 28 days following i.p. bleomycin (Bleo) treatment. (B) Flow cytometric analysis of circulating blood fibrocytes (CD45+, Col I+) on day 28 following i.p. Bleo treatment. (C) Flow cytometric analysis of lung fibrocytes (CD45+, Col I+) 42 days following i.p. Bleo treatment. (D) Total lung collagen 42 days following i.p. Bleo treatment. Error bars represent one standard deviation of the mean. Experiments were performed 4 times with 5 mice per group (A and B). Experiments were performed 3 times with 10 mice per group (C and D). Paired Student’s t test were performed on samples with ANOVA. P < 0.05. Col I, collagen I.