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. 2016 Apr 7;1(4):e83116. doi: 10.1172/jci.insight.83116

Figure 7. Lung-resident memory CD4+ T cells are required for the vaccinia vaccination to mitigate fibrosis.

Figure 7

(A) Flow cytometric analysis of circulating vs. protected CD4+ T cells on day 42 following i.p. bleomycin (Bleo) with or without vaccinia vaccine treatment and T cell depletion. (B) Flow cytometric analysis of lung fibrocytes. (C) Total lung collagen on day 42 following i.p. Bleo. Error bars represent one standard deviation of the mean. Experiments were performed 3 times with 5 mice per group. Significance determined by 1-way ANOVA followed by Tukey’s test when indicated.