Skip to main content
. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: JAMA. 2013 Jan 2;309(1):71–82. doi: 10.1001/jama.2012.113905

Table 2.

Summary Hazard Ratios (HRs) of All-Cause Mortality for Overweight and Obesity Relative to Normal Weight From Studies Considered Adequately Adjusted

Self-reported or Measured Height and Weight Height and Weight

Measured Self-reported



No. of HRs Summary HR (95% CI) I2, % No. of HRs Summary HR (95% CI) I2, % No. of HRs Summary HR (95% CI) I2, %
BMI of 25–<30
 All ages 86 0.94 (0.90–0.97)a 87.6 45 0.92 (0.88–0.96)a 74.8 41 0.95 (0.90–1.01)a 91.0

 Mixed ages 68 0.95 (0.91–0.99)a 89.3 34 0.93 (0.88–0.98)a 79.2 34 0.96 (0.91–1.02)a 91.8

 Age ≥65 y only 18 0.90 (0.86–0.95) 27.9 11 0.90 (0.84–0.96) 23.4 7 0.91 (0.84–0.98) 42.9

BMI of ≥30
 All ages 42 1.21 (1.12–1.31)a 89.3 22 1.11 (1.03–1.20)a 67.1 20 1.33 (1.21–1.47)a 88.0

 Mixed ages 33 1.26 (1.16–1.37)a 89.7 16 1.13 (1.04–1.23)a 66.7 17 1.39 (1.27–1.53)a 84.3

 Age ≥65 y only 9 1.05 (0.92–1.21)a 63.9 6 1.02 (0.81–1.29)a 73.1 3 1.08 (0.93–1.25) 39.7

BMI of 30–<35
 All ages 42 0.97 (0.90–1.04)a 83.8 21 1.00 (0.92–1.09)a 64.2 21 0.94 (0.84–1.05)a 89.6

 Mixed ages 33 0.98 (0.91–1.06)a 84.8 16 1.03 (0.94–1.12)a 64.8 17 0.95 (0.85–1.07)a 90.3

 Age ≥65 y only 9 0.88 (0.69–1.12)a 78.0 5 0.90 (0.70–1.16)a 64.1 4 0.82 (0.46–1.47)a 88.1

BMI of ≥35
 All ages 42 1.34 (1.21–1.47)a 81.2 21 1.32 (1.20–1.46)a 46.6 21 1.35 (1.16–1.57)a 88.7

 Mixed ages 33 1.35 (1.22–1.50)a 82.2 16 1.37 (1.24–1.52) 40.4 17 1.34 (1.14–1.57)a 89.6

 Age ≥65 y only 9 1.28 (0.93–1.76)a 75.2 5 1.12 (0.89–1.43) 37.8 4 1.40 (0.64–3.07)a 86.8

Abbreviation: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared).

a

Indicates significant heterogeneity (P<.05).