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. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: Neuropharmacology. 2015 Oct 19;101:490–505. doi: 10.1016/j.neuropharm.2015.10.020

Figure 9. Effects of caffeine and DPCPX in the absence of dopamine on locomotor-related output parameters.

Figure 9

A: time-course plots from a locomotor rhythm elicited with 5-HT and NMDA in the absence of dopamine showing no effects in locomotor burst amplitude, burst duration or cycle period after the application of caffeine (50μM; 20 minutes; n = 4). Each point represents 1 minute worth of recording. B: pooled data, average of 5 minutes worth of recordings in each condition, showing no significant effects on any of the parameters measured after the application of caffeine in the absence of dopamine (n = 4). C: time-course plots from a locomotor rhythm elicited with 5-HT and NMDA in the absence of dopamine showing no effects in locomotor burst amplitude, burst duration or cycle period after the application of the A1 adenosine receptor antagonist DPCPX (1μM; 20 minutes; n = 4). Each point represents 1 minute worth of recording. D: pooled data, average of 5 minutes worth of recording in each condition, showing no significant effects on any of the parameters measured after the application of DPCPX in