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. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: Hepatology. 2010 Apr;51(4):1410–1419. doi: 10.1002/hep.23450

Table 1.

Previously Reported FXR Binding Sites Detected by ChIP-Seq

Gene Binding Site Peak Value Tissue
Nr0b2 −320 to −220 bp upstream of TSS 258; 124 Liver; intestine
Abcb11 −240 to −140 bp upstream of TSS 308 Liver
Fgf15 1880–1980 bp with in an intron 43; 273 Liver; intestine
Osta −1245 to −1145 bp upstream of TSS 502 Intestine
Ostb −220 to −150 bp upstream of TSS 271; 572 Liver; intestine
Fabp6 site 1: −220 to −120; site 2: −2990 to −2890;
  and site 3: −7600 to −7500 bp upstream		 540, 638, 93 Intestine