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. 2016 Apr 11;113(17):4824–4829. doi: 10.1073/pnas.1517558113

Table S2.

Subject demographic and clinical information

Demographic BD HC
BD TOT Manic BD Depressed BD Euthymic BD
Sample size n (%) 60 (100) 20 (33.3) 20 (33.3) 20 (33.3) 40 (100)
Age (y) mean (SD) 44.7 (11.2) 46 (12) 44.9 (10.9) 43.1 (11) 43.9 (12.8)
Female n (%) 42 (70) 17 (85) 13 (65) 12 (60) 26 (65)
Age of onset mean (SD) 25 (10.8) 25 (12.3) 25.3 (9.8) 24.6 (10.9)
Duration of illness mean (SD) 19.9 (11.6) 21.7 (14.5) 19.5 (10.8) 18.2 (9)
HAM-D mean (SD) 7 (5.4) 21.5 (4) 3.6 (2.8)
YMRS mean (SD) 19 (5.7) 4.2 (2.8) 3.9 (2.7)
Mood stabilizers n (%) 52 (86.7) 16 (80) 18 (90) 18 (90)
Lithium n (%) 16 (26.7) 4 (20) 5 (25) 7 (35)
Valproate n (%) 26 (43.3) 10 (50) 8 (40) 8 (40)
Other antiepileptic drugs n (%) 23 (38.3) 5 (25) 9 (45) 9 (45)
Antidepressants n (%) 22 (36.7) 2 (10) 11 (55) 9 (45)
SRI n (%) 10 (16.7) 1 (5) 6 (30) 3 (15)
Tricyclic antidepressants n (%) 6 (10) 0 (0) 4 (20) 2 (10)
Duals and other antidepressants n (%) 10 (16.7) 1 (5) 4 (20) 5 (25)
Antipsychotics n (%) 34 (56.7) 14 (70) 12 (60) 9 (45)
Atypical n (%) 29 (48.3) 10 (50) 13 (65) 6 (30)
Typical n (%) 7 (11.7) 5 (25) 1 (5) 1 (5)
Benzodiazepines n (%) 20 (33) 5 (25) 7 (35) 8 (40)
Unmedicated n (%) 2 (3.3) 1 (5) 0 (0) 1 (5)

SRI, serotonin reuptake inhibitors.