. 2016 Apr 11;113(17):E2363–E2372. doi: 10.1073/pnas.1517066113

Table S1.

Permeability ratios of TRPP2_F604P and the listed mutant channels

Channel type	Na⁺		DMA⁺		TMA⁺		Tris⁺
Channel type	ΔE_rev ± SD (n)	P_Na/P_NMDG	ΔE_rev ± SD (n)	P_DMA/P_NMDG	ΔE_rev ± SD (n)	P_TMA/P_NMDG	ΔE_rev ± SD (n)	P_Tris/P_NMDG
F604P	23.85 ± 5.49 (7)	2.5	22.67 ± 7.02 (3)	2.0	12 ± 5.9 (4)	1.9	7.57 ± 5.41 (7)	1.3
F604P_D643N	27.75 ± 4.19 (4)	3.3	29.67 ± 6.50 (3)	3.0	24 ± 2 (3)	2.6	4.67 ± 2.31 (3)	1.4
F604P_D643Q	21.5 ± 5.64 (10)	2.3	16.86 ± 2.67 (7)	2.0	10.75 ± 1.70 (4)	2.1	7.57 ± 2.88 (7)	1.2
F604P_E648K	26.5 ± 5.02 (5)	2.8	26.5 ± 2.12 (2)	2.3	20.6 ± 6.31 (5)	2.2	12.8 ± 6.61 (5)	1.7
F604P_E648Q	23.8 ± 5.40 (5)	2.4	24.67 ± 2.51 (3)	2.4	16.2 ± 4.66 (5)	1.9	4.17 ± 2.99 (6)	1.2

ΔE_rev is the change of reversal potential of currents in 100 mM NMDG⁺ and 100 mM tested ions (ΔE_rev = E_rev,X ₋ E_rev,NMDG). Statistical analysis of the reversal potential is given in Fig. 4B. Results are shown as the mean and SD. n, number of measurements.