Figure 1.

Immunolocalisation of tRFP635 and AR, and testicular and epididymal morphology in virus‐injected adult testes. A–B: Sertoli cells retain AR expression (white arrows) following injection of control virus (A), whereas injection of Cre‐encoding virus induces Sertoli cell‐specific ablation of AR (B). C–F: Normal testicular (C) and epididymal (E) morphology was observed in controls. Loss of Sertoli‐cell AR following Cre‐encoding virus injection leads to meiotic arrest (D), which resulted in an absence of spermatozoa in the epididymis (F).