Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Apr 7;7(4):e2174. doi: 10.1038/cddis.2016.73

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Signaling pathways involved in KCa3.1 channel activation. (a) Levels of pFAK/FAK and pAKT/AKT in NCM- and GCM-treated microglia in the absence (C) or presence of TRAM-34 (T, 2.5 μM). Data are the mean±S.E.M., *P<0.05 versus NCM; ^#P<0.05 versus GCM/C; N=5. Representative blots are shown on the top. Actin was used as a loading control, and molecular markers are indicated on the left (KDa). (b) Migration, invasion and phagocytosis assays on NCM- and GCM-treated microglia in the absence (C) or presence of PF-228 (PF, 10 μM) or LY294002 (LY, 25 μM). Data are the mean±S.E.M., *P<0,05 versus NCM; ^#P<0.05 versus GCM/C; N=4. (c) Levels of pFAK/FAK and pAKT/AKT in untreated or SKA-31-treated (250 nM) microglia in the absence (C) or presence of PF-228 (PF, 10 μM) or LY294002 (LY, 25 μM). Data are shown as mean±S.E.M.; *P<0.05 versus NCM; ^#P<0.05 versus GCM/C; N=8. Top: representative blots are shown on the top. Actin was used as a loading control, and molecular markers are indicated on the left (KDa)