Figure 1.

Impact of GABARAP deficiency on the mice upon DMBA treatment. (a) Size of all the tumors induced by DMBA in Wt and GABARAP KO mice. (b) Representative picture of the spleens removed from Wt and GABARAP KO mice at the same age (14 weeks) and treatment condition. (c) Spleen weights for vehicle-treated (control) and DMBA-treated mice (14 weeks). (d) Total number of splenocytes. The data were calculated using three mice per group and shown as means±S.E.M. (e and f), Quantitative analysis and immunofluorescence TUNEL staining of spleen sections. The data were calculated using 3–6 mice per group and shown as means±S.E.M. Scale bars=100 μm. *P<0.05, **P<0.01, ***P<0.001