FIG. 1.

mRNA expression of HIF-2α and EPO, as measured using real-time quantitative polymerase chain reaction, was higher in the BMMNCs of CMS patients than in the controls. (A) mRNA expression of HIF-1α and HIF-2α. (B) mRNA expression of EPO and EPOR. Data are presented as mean ± SEM. The statistical differences from the controls were calculated using the t-test after log transformation. *p < 0.05. **p < 0.001. BMMNC, bone marrow mononuclear cell; CMS, chronic mountain sickness; EPO, erythropoietin; EPOR, erythropoietin receptor; HIF, hypoxia-inducible factor.