Table 3.
Relevant in vitro dose (RID) functions for nCeO2, amsCeO2, and aSiO2 nanoparticles when dispersed in FGM
| Nanomaterial | M | N | SA | RIDM | RIDN | RIDSA |
|---|---|---|---|---|---|---|
| nCeO2 Low dose | 0.01 | 2.08E-09 | 3.63E-16 | 0.01 | 1.08E-16 | 1.88E-23 |
| nCeO2 High dose | 0.40 | 4.25E-01 | 4.53E-01 | 0.36 | 2.20E-08 | 2.35E-08 |
| amsCeO2 Low dose | 0.01 | 6.82E-10 | 3.90E-17 | 0.01 | 5.88E-17 | 3.37E-24 |
| amsCeO2 High dose | 0.40 | 3.10E-01 | 2.41E-01 | 0.39 | 2.68E-08 | 2.08E-08 |
| aSiO2 Low dose | 0.01 | 6.56E-11 | 9.69E-05 | 0.01 | 3.11E-18 | 4.60E-12 |
| aSiO2 High dose | 0.40 | 1.10E + 00 | 1.62E + 06 | 0.39 | 5.20E-08 | 7.68E-02 |
Delivered dose values based on delivered ENM mass (M), delivered particle number (N), and delivered surface area (SA) for either a high (0.57 μg/mL, equivalent to 0.2 μg/cm2 for this study) or low (0.017 μg/mL, 0.006 μg/cm2) dose