. Author manuscript; available in PMC: 2016 May 4.

Published in final edited form as: Curr Treat Options Oncol. 2015 Aug;16(8):36. doi: 10.1007/s11864-015-0356-2

Table 2.

Selected dietary supplement clinical trials in patients with primary brain tumors

Dietary supplement/substance	Preclinical	Phase I	Phase II
Copper and penicillamine	X [54–56]		X [57]
Vitamin A/retinoids	X [58]		X [59, 60, 61••]
Vitamin D/vitamin D analogs	X[62]		X [63]
Vitamin C/ascorbic derivatives	X[64]
Curcumin and turmeric	X [66–68]
Boswellic acid/frankincense	X [70]
Selenium	X [73, 74]	X [75]

Summary of preclinical and clinical (phase I, II, and III) trials conducted for selected dietary supplements