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. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: Biopolymers. 2015 Jul;104(4):334–350. doi: 10.1002/bip.22639

FIGURE 1.

FIGURE 1

Schematic illustration of a systematic, minimal approach to the design of the four-helix bundle protein. From Regan, L.; DeGrado, W. F. Science 1988, 241, 976–978. Reprinted with permission from AAAS.