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. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: Am Heart J. 2014 Sep 16;168(6):917–923. doi: 10.1016/j.ahj.2014.08.008

Table 3.

Factors Associated with Severity of Cognitive Impairment (CI)

Characteristic Number of Domains Impaired
1 2 3
N=224 N=215 N=114

OR (95% CI)
Age
 <65 (Referent) (Referent) (Referent)
 65–74 0.83 (0.46–1.52) 2.56 (1.30–5.03) 4.34 (1.71–10.98)
 75–84 1.50 (0.80–2.82) 5.77 (2.85–11.68) 12.22 (4.89–30.58)
 ≥85 3.82 (1.48–9.88) 22.44 (8.36–60.21) 65.82 (20.22–214.28)
 Female 0.51 (0.31–0.82) 0.31 (0.18 – 0.51) 0.18 (0.10 – 0.33)
 White race 1.43 (0.68–3.02) 0.89 (0.41–1.96) 0.48 (0.20–1.15)
Education
 < High school (Referent) (Referent) (Referent)
 High school/some college 0.68 (0.31–1.48) 0.23 (0.10–0.49) 0.18 (0.08–0.41)
 ≥ College graduate 0.31 (0.15–0.67) 0.10 (0.05–0.21) 0.04 (0.02–0.11)
Depression 1.56 (0.96–2.55) 1.52 (0.91–2.55) 1.98 (1.08–3.64)
Hospitalized w/in 3 months for HF 0.69 (0.42–1.14) 0.99 (0.59–1.65) 0.84 (0.46–1.53)
Confidence recognizing changes in health, very/extremely confident 0.66 (0.39–1.16) 0.87 (0.49–1.54) 0.75 (0.38–1.47)
Confidence recognizing symptoms of HF, very/extremely confident 0.79 (0.60–1.03) 1.01 (0.76–1.34) 0.88 (0.62–1.26)
Confidence recognizing symptoms requiring medical contact, very/extremely confident§ 0.93 (0.52–1.65) 0.89 (0.49–1.64) 0.55 (0.27–1.12)
Confidence recognizing symptoms requiring 911, very/extremely confident 1.66 (0.90–3.08) 1.17 (0.62–2.22) 1.25 (0.61–2.58)
Total cardiac comorbid conditions 0.97 (0.83–1.13) 1.00 (0.85–1.18) 1.00 (0.82–1.22)
Total non-cardiac comorbid conditions 1.36 (1.06–1.75) 1.27 (0.98–1.66) 1.16 (0.84–1.60)
Clinical exam findings
 Pulmonary rales 1.70 (0.95–3.03) 1.45 (0.78–2.68) 1.41 (0.66–3.03)

Referent group consists of those patients with no cognitive impairment