Raw data show samples of continuous mEPSC recordings collected from dorsal horn neurons of AMPKα1 knockout mice before, during and after washout of PBN (A) or CoPP (D) perfusion. Bar graphs show the mean (+ S.E.) frequency and amplitude of mEPSCs in AMPKα1 knockout mice before (baseline), during and after washout of PBN (B and C) or CoPP (E and F). *, p < 0.05; **, p < 0.01; ***, p < 0.001.