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APC/C destruction motifs.
| Destruction motif | Sequence | References |
|---|---|---|
| D box | RxxLxxxN | Glotzer et al., 1991 |
| KEN box | KENxxxN | Pfleger Kirschner, 2000 |
| A box or DAD (D box activating domain) |
RxLxPSN | Castro et al., 2002; Littlepage Ruderman, 2002 |
| CRY box | CRYxPS | Reis et al., 2006 |
| GxEN | GxEN | Castro et al., 2003 |
| O box | LxEKN | Araki et al., 2005 |
| Spo13 | LxExxxN | Sullivan Morgan, 2007 |
| TEK box | R/KxxTxKT | Jin et al., 2008 |
“x” indicates any amino acid.
