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. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: J Med Chem. 2015 Dec 16;59(1):206–218. doi: 10.1021/acs.jmedchem.5b01268

Table 2.

Biodistribution of [18F]12 in Tumor Bearing Micea

30 minb 60 minc 90 minc 180 minc
blood 2.51 ± 1.75 1.07 ± 0.26 0.20 ± 0.14 0.08 ± 0.06
heart 1.12 ± 0.74 0.25 ± 0.08 0.11 ± 0.02 0.07 ± 0.04
lung 2.07 ± 1.51 0.85 ± 0.55 0.33 ± 0.05 0.14 ± 0.04
liver 11.0 ± 1.77 12.5 ± 3.01 11.0 ± 0.87 4.62 ± 3.80
spleen 3.76 ± 6.48 0.45 ± 0.31 0.27 ± 0.04 0.13 ± 0.08
fat 1.23 ± 1.88 0.15 ± 0.05 0.11 ± 0.06 0.04 ± 0.02
kidney 14.2 ± 8.47 6.97 ± 7.02 1.51 ± 0.22 0.50 ± 0.18
small
intestine
1.89 ± 1.58 0.54 ± 0.19 0.27 ± 0.11 0.08 ± 0.04
large
intestine
3.82 ± 5.87 0.62 ± 0.27 0.18 ± 0.03 0.16 ± 0.05
muscle 0.86 ± 0.81 0.27 ± 0.12 0.06 ± 0.01 0.03 ± 0.01
bone 2.05 ± 2.39 0.72 ± 0.31 0.79 ± 0.16 0.63 ± 0.14
bladder 22.4 ± 22.5 5.50 ± 3.45 2.11 ± 1.21 2.74 ± 0.48
PC-3 Pip 6.33 ± 1.55 3.52 ± 1.48 0.94 ± 0.24 0.22 ± 0.07
PC-3 flu 1.89 ± 0.78 0.72 ± 0.12 0.37 ± 0.08 0.12 ± 0.03
a

Values expressed as percent injected dose per gram ± standard deviation.

b

N = 7.

c

N = 4.