Table 3. Networks identified by BlocBuster using a threshold of CCC ≥ 0.65 on the samples described in Table 1 and the SNPs described in File S1.

Network	Gene	Network ID	SNP	Allele	Chr	Gene Location
65_1	TYRP1	70_1	rs2733832	C	9	Intron 5
			rs1408799	T		5′UTR
	VDR	70_5	rs4760658	T	12	Promoter (Intron 1a)
			rs11168293	C
			rs2853564	T
			rs1989969	C
	TYR	n/a	rs1042602	C	11	Ser192Tyr
65_2	VDR	70_4	rs11568820	G	12	Promoter (Cdx2)
			rs10875695	G		Promoter (Intron 1a)
			rs7302235	A		Promoter (Intron 1a)
	VDR	n/a	rs4073729	C	12	Promoter
	MC1R	n/a	rs2228478	A	16	Thr314Thr
	MC1R	n/a	rs3212369	A	16	3′UTR
	SLC24A5	n/a	rs1426654	A	15	Thr111Ala
	SLC45A2	n/a	rs16891982	G	5	Phe374Leu
65_3	MC1R	70_3	rs3212357	T	16	5′UTR
			rs3212359	C		5′UTR
	MC1R	n/a	rs3212363	A	16	5′UTR
65_4	VDR	n/a	rs4237856	T	12	Promoter
	VDR	n/a	rs10783219	A	12	Promoter (Intron 1a)
	VDR	n/a	rs2238136	G	12	Promoter (Intron 1a)
65_5	VDR	70_6	rs2248098	T	12	Intron 3
			rs1544410	G		Intron 8
			rs731236	T		Exon 9
			rs3782905	C		Intron 2
			rs2238138	C		Intron 2
	VDR	70_8	rs739837	C	12	3′ UTR
			rs7975232	G		Intron 8
65_6	VDR	70_7	rs7305032	T	12	Intron 5
			rs7975232	T		Intron8
			rs2525044	C		Intron6
			rs739837	A		3′ UTR
	VDR	n/a	rs2248098	C	12	Intron 3
65_7	MC1R	70_2	rs3212357	C	16	5′UTR
	MC1R		rs3212359	T		5′UTR

Components at a threshold of CCC ≥ 0.70 are indicated by 70_x in the Network ID column. SNP, single nucleotide polymorphism; Chr, chromosome; UTR, untranslated region; Ser, serine; Tyr, tyrosine; Thr, threonine; Ala, alanine; Phe, phenylalanine; Leu, leucine.