Table 1. Proportion of genes in each Cormotif pattern containing vitamin D receptor (VDR) binding sites.
Cormotif Pattern | Total No. Genes | No. Genes with VDR Binding Site | Proportion of Genes with VDR Binding Site | Enrichment P Value |
---|---|---|---|---|
No response | 5737 | 186 | 0.03 | — |
All | 265 | 31 | 0.12 | 2.57 × 10−8 |
All except V + L | 1364 | 65 | 0.05 | 0.01 |
1,25D | 350 | 17 | 0.05 | 0.13 |
1,25D + LPS | 270 | 23 | 0.09 | 1.49 × 10−4 |
1,25D-all | 782 | 76 | 0.10 | 6.88 × 10−13 |
LPS | 2026 | 96 | 0.05 | 3.79 × 10−3 |
Interethnic | 164 | 8 | 0.05 | 0.27 |
Enrichment of VDR peaks in each category was calculated using Fisher’s exact test, comparing genes in each Cormotif pattern to those in the “No response” Cormotif pattern.