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. 2016 Mar 7;5:291. [Version 1] doi: 10.12688/f1000research.8182.1

Table 1. List of datasets constituting the collection.

Title Platforms Diseases Number of
sample
Experiments GEO ID References
Interaction of bone marrow stroma and monocytes: bone marrow
stromal cell lines cultured with monocytes
Affymetrix Healthy 8 In vitro GSE10595 37
Monocyte gene expression profiling in familial combined
hyperlipidemia and its modification by atorvastatin treatment
Affymetrix Familial combined
hyperlipidemia
9 In vitro GSE11393 38
Performance comparison of Affymetrix and Illumina microarray
technologies
Affymetrix Acute coronary syndrome 10 Ex vivo GSE11430 39
Gene expression profiling in pediatric meningococcal sepsis
reveals dynamic changes in NK-cell and cytotoxic molecules
Affymetrix Meningococcal sepsis 41 Ex vivo GSE11755 N/A
Effect of interferon-gamma on macrophage differentiation and
response to Toll-like receptor ligands
Affymetrix Healthy 10 In vitro GSE11864 40
Human monocyte and dendritic Cell Subtype Gene Arrays Affymetrix Healthy 8 Ex vivo GSE11943 41
Microarray analysis of human monocytes infected with Francisella
tularensis
Affymetrix Healthy 14 In vitro GSE12108 42
Human blood monocyte profile in Ventilator-Associated Pneumonia
patients
Affymetrix Pneumonia 60 Ex vivo GSE12838 N/A
Quercetin supplementation and CD14+ monocyte gene expression Affymetrix Healthy 6 Ex vivo GSE13899 43
Effects of PMN-Ectosomes on human macrophages Affymetrix Healthy 16 In vitro GSE14419 N/A
Homogeneous monocytes and macrophages from hES cells
following coculture-free differentiation in M-CSF and IL-3
Affymetrix Healthy 9 Ex vivo GSE15791 44
Expression data from human macrophages Affymetrix Healthy 38 In vitro GSE16385 45
Transcriptional profiling of CD16+ and CD16- peripheral blood
monocytes from healthy individuals
Affymetrix Healthy 8 Ex vivo GSE16836 32
COPD-Specific Gene Expression Signatures of Alveolar
Macrophages as well as Peripheral Blood Monocytes Overlap and
Correlate with Lung Function
Affymetrix Chronic obstructive
pulmonary disease
12 Ex vivo GSE16972 46
Loss-of-function mutations in REP-1 affect intracellular vesicle
transport in fibroblasts and monocytes of CHM patients
Affymetrix Choroideremia 15 Ex vivo GSE17549 47
Effect of two weeks erythropoietin treatment on monocyte
transcriptomes of cardiorenal patients
Illumina Cardiorenal syndrome 48 Ex vivo GSE17582 N/A
Comparison of gene expression profiles between human
monocyte subsets
Affymetrix Healthy 6 Ex vivo GSE18565 48
Subpopulations of CD163 positive macrophages are classically
activated in psoriasis
Illumina Psoriasis 58 Ex vivo GSE18686 49
Mycobacterium tuberculosis Chaperonin 60.1 has Bipolar Effects
on Human peripheral blood-derived Monocytes
Affymetrix Healthy 21 In vitro GSE18794 N/A
Blood Transcriptional Profiles of Active TB (Separated cell) Illumina Tuberculosis 44 Ex vivo GSE19443 11
Filaria induced monocyte dysfunction and its reversal following
treatment
Affymetrix Filariasis 14 Ex vivo GSE2135 50
Ubiquinol-induced gene expression signatures are translated into
reduced erythropoiesis and LDL cholesterol levels in humans
Affymetrix Healthy 6 Ex vivo GSE21351 51
Monocyte vs Macrophage Study Affymetrix Healthy 6 In vitro GSE22373 52
Monocyte gene expression patterns distinguish subjects with and
without atherosclerosis
Illumina Carotid atherosclerosis 95 Ex vivo GSE23746 N/A
Deconvoluting Early Post-Transplant Immunity Using Purified Cell
Subsets Reveals Functional Networks Not Evident by Whole Blood
Analysis
Affymetrix Kidney transplantation 179 Ex vivo GSE24223 53
Cooperative and redundant signaling of leukotriene B4 and
leukotriene D4 in human monocytes
Affymetrix Healthy 10 In vitro GSE24869 54
Gene expression profiling of the classical (CD14++CD16-),
intermediate (CD14++CD16+) and nonclassical (CD14+CD16+)
human monocyte subsets
Illumina Healthy 24 Ex vivo GSE25913 34
Direct Cell Conversion of Human Fibroblasts to Monocytic
phagocytes by Forced Expression of Monocytic Regulatory
Network Elements
Illumina Dermatomyositis 15 Ex vivo GSE27304 N/A
cMyb and vMyb in human monocytes Affymetrix Healthy 6 In vitro GSE2816 55
Temporal transcriptional changes in human monocytes following
acute myocardial infarction: The GerMIFs monocyte expression study
Illumina Acute myocardial
infarction
76 Ex vivo GSE28454 N/A
mRNA expression profiling of human immune cell subset (Roche) Affymetrix Healthy 47 Ex vivo GSE28490 56
mRNA expression profiling of human immune cell subsets (HUG) Affymetrix Healthy 33 Ex vivo GSE28491 56
Changes in gene expression profiles in patients with 5q- syndrome
in CD14+ monocytes caused by lenalidomide treatment
Illumina 5q- syndrome 17 Ex vivo GSE31460 N/A
Genome-wide analysis of lupus immune complex stimulation of
purified CD14+ monocytes and how this response is regulated by C1q
Illumina Healthy 8 In vitro GSE32278 57
Transcriptome analysis of circulating monocytes in obese patients
before and three months after bariatric surgery
Illumina Obesity 48 Ex vivo GSE32575 58
CD4 on human monocytes Affymetrix Healthy 6 In vitro GSE32939 59
Peripheral Blood Monocyte Gene Expression in Recent-Onset
Type 1 Diabetes
Illumina Type 1 Diabetes 22 Ex vivo GSE33440 60
Traffic-related Particulate Matter Upregulates Allergic Responses
by a Notch-pathway Dependent Mechanism
Affymetrix Healthy 16 In vitro GSE34025 N/A
Human monocyte activation with NOD2L vs. TLR2/1L Affymetrix Healthy 45 In vitro GSE34156 61
Bacillus anthracis' lethal toxin induces broad transcriptional
responses in human peripheral monocyte
Affymetrix Healthy 8 In vitro GSE34407 62
Gene expression profiles of human blood classical monocytes
(CD14++CD16-), CD16 positive monocytes (CD14+16++ and
CD14++CD16+), and CD1c+ CD19- dendritic cells
Affymetrix Healthy 9 Ex vivo GSE34515 N/A
Genome-wide analysis of monocytes and T cells' response to
interferon beta
Illumina Healthy 12 In vitro GSE34627 63
Highly pathogenic influenza virus inhibit Inflammatory Responses
in Monocytes via Activation of the Rar-Related Orphan Receptor
Alpha (RORalpa)
Affymetrix Healthy 12 In vitro GSE35283 N/A
Transcriptome profiles of human monocyte and dendritic cell subsets Illumina Healthy 49 Ex vivo GSE35457 64
Influenza virus A infected monocytes Illumina Healthy 6 In vitro GSE35473 65
PGE2-induced OSM expression Affymetrix Chronic wound 6 Ex vivo GSE36995 66
Inflammatory Expression Profiles in Monocyte to Macrophage
Differentiation amongst Patients with Systemic Lupus
Erythematosus and Healthy Controls with and without an
Atherosclerosis Phenotype
Illumina Systemic lupus
erythematosus
72 Ex vivo GSE37356 N/A
New insights into key genes and pathways involved in the
pathogenesis of HLA-B27-associated acute anterior uveitis
Affymetrix Acute anterior uveitis 6 In vitro GSE37588 N/A
Analysis of blood myelomonocytic cells from RCC patients Illumina Renal cell carcinoma 8 Ex vivo GSE38424 67
Nanotoxicogenomic study of ZnO and TiO2 responses Illumina Healthy 90 In vitro GSE39316 N/A
Macrophage Microvesicles Induce Macrophage Differentiation
and miR-223 Transfer
Affymetrix Healthy 24 In vitro GSE41889 68
TREM-1 is a novel therapeutic target in Psoriasis Affymetrix Psoriasis 15 In vitro GSE42305 69
Comparison study between Uremic patient with Healthy control Affymetrix Chronic kidney disease 6 Ex vivo GSE43484 N/A
Microarray analysis of IL-10 stimulated adherent peripheral blood
mononuclear cells
Affymetrix Healthy 8 In vitro GSE43700 70
Monocytes and Dendritic cells stimulated by 13 human vaccines
and LPS
Illumina Vaccination 128 In vitro GSE44721 36
Gene expression profile of human monocytes stimulated with
all-trans retinoic acid (ATRA) or 1,25a-dihydroxyvitamin D3 (1,25D3)
Affymetrix Healthy 12 In vitro GSE46268 71
Transcriptome analysis of blood monocytes from sepsis patients Illumina Sepsis 44 Ex vivo GSE46955 72
Tumor-educated circulating monocytes are powerful specific
biomarkers for diagnosis of colorectal cancer
Illumina Colorectal cancer 93 Ex vivo GSE47756 73
Similarities and differences between macrophage polarized gene
profiles
Illumina Healthy 12 In vitro GSE49240 74
The effect of cell subset isolation method on gene expression in
leukocytes.
Illumina Healthy 50 Ex vivo GSE50008 N/A
Transcriptome analysis of HIV-infected peripheral blood
monocytes
Illumina HIV 86 Ex vivo GSE50011 75
Gene expression profiles in T-lymphocytes and Monocytes of
participants of the Tour de France 2005
Affymetrix Healthy 66 Ex vivo GSE5105 N/A
Effects of exercise on gene expression level in human monocytes Affymetrix Healthy 24 Ex vivo GSE51835 76
T helper lymphocyte- and monocyte-specific type I interferon (IFN)
signatures in autoimmunity and viral infection.
Affymetrix Autoimmune diseases 36 Ex vivo GSE51997 77
Longitudinal comparison of monocytes from an HIV viremic vs
avirmeic state
Affymetrix HIV 16 Ex vivo GSE5220 78
Expression data from monocytes and monocyte derived
macrophages
Affymetrix Healthy 12 In vitro GSE52647 N/A
Transcriptome analysis of primary monocytes from HIV+ patients
with differential responses to therapy
Illumina HIV 14 Ex vivo GSE52900 79
Human blood monocyte response to IL-17A in culture Affymetrix Healthy 6 In vitro GSE54884 N/A
Divergent genome wide transcriptional profiles from immune
cell subsets isolated from SLE patients with different ancestral
backgrounds
Illumina Systemic lupus
erythematosus
208 Ex vivo GSE55447 80
Cell Specific Expression & Pathway Analyses Reveal Novel
Alterations in Trauma-Related Human T-Cell & Monocyte Pathways
Affymetrix Trauma patients 42 Ex vivo GSE5580 81
Immune Variation Project (ImmVar) [CD14] Affymetrix Healthy 485 Ex vivo GSE56034 N/A
Transcriptomics of human monocytes Illumina Healthy 1202 Ex vivo GSE56045 82
Effect of vitamin D treatment on human monocyte Affymetrix Healthy 16 In vitro GSE56490 N/A
Monocytes of patients with familial hypercholesterolemia show
alterations in cholesterol metabolism
Affymetrix Hypercholesterolemia 23 Ex vivo GSE6054 83
Gene expression data from CD14++ CD16- classical monocytes
from healthy volunteers and patients with pancreatic ductal
adenocarcinoma
Affymetrix Pancreatic ductal
adenocarcinoma
12 Ex vivo GSE60601 N/A
Activation of the JAK/STAT pathway in Behcet's Disease Affymetrix Behcet’s disease 29 Ex vivo GSE61399 N/A
Alarmins MRP8 and MRP14 induce stress-tolerance in phagocytes
under sterile inflammatory conditions
Illumina Sterile inflammation 12 In vitro GSE61477 N/A
GM-CSF induced gene-regulation in human monocytes Affymetrix Healthy 6 In vitro GSE63662 84
Treatment of human monocytes with TLR7 or TLR8 agonists Affymetrix Healthy 9 In vitro GSE64480 85
Restricted Dendritic Cell and Monocyte Progenitors in Human
Cord Blood and Bone Marrow
Illumina Healthy 36 Ex vivo GSE65128 86
Interleukin-1- and Type I Interferon-Dependent Enhanced
Immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef Vaccine
Vector with Dual Deletions of Type I and Type II Interferon-Binding
Proteins
Illumina Vaccination 20 In vitro GSE65412 N/A
Comparative analysis of monocytes from healthy donors, patients
with metastatic breast cancer, sepsis or tuberculosis.
Illumina Breast cancer and
Bacterial infection
13 Ex vivo GSE65517 87
Expression data from intermediate monocytes from healthy donors
and autoimmune uveitis patients
Affymetrix Autoimmune uveitis 21 Ex vivo GSE66936 88
Induction of Dendritic Cell-like Phenotype in Macrophages during
Foam Cell Formation
Affymetrix Healthy 22 In vitro GSE7138 89
Genome Wide Gene Expression Study of Circulating Monocytes in
human with extremely high vs. low bone mass
Affymetrix Healthy 26 Ex vivo GSE7158 N/A
Genomic profiles for human peripheral blood T cells, B cells,
natural killer cells, monocytes, and polymorphonuclear cells:
comparisons to ischemic stroke, migraine, and Tourette syndrome
Affymetrix Healthy 18 Ex vivo GSE72642 90
Expression data from monocytes of individuals with different
collateral flow index CFI
Affymetrix Coronary artery disease 160 Ex vivo GSE7638 91
Leukotriene D4 induces gene expression in human monocytes
through cysteinyl leukotriene type I receptor
Affymetrix Healthy 8 In vitro GSE7807 92
Gene expression profile during monocytes to macrophage
differentiation
Affymetrix Healthy 9 In vitro GSE8286 N/A
Toll-like receptor triggering of a vitamin D-mediated human
antimicrobial response
Affymetrix Healthy 50 In vitro GSE8921 93
TRAIL Is a Novel Antiviral Protein against Dengue Virus Affymetrix Dengue 10 In vitro GSE9378 N/A
Gene Expression-Based High Throughput Screening: APL
Treatment with Candidate Compounds
Affymetrix Leukemia 24 Ex vivo GSE976 94
Innate immune responses to TREM-1 activation Affymetrix Healthy 11 In vitro GSE9988 95