Table I.
Demographics and Baseline Characteristics of Patients with SCD and Controls
| Variable | SCD Patients (n=55) | Controls (n=57) | p-value |
|---|---|---|---|
| Age (years) | |||
| Mean (±SD) | 15.4 (±6.3) | 16.3 (±10.2) | 0.59 |
| Median (IQR) | 14 (11-19) | 12 (9-18) | 0.42 |
| Gender | |||
| Female | 33 (60%) | 32 (56%) | 0.68 |
| Sickle Cell Genotype | N/A | N/A | |
| HbSS | 37 (67%) | ||
| HbSC | 10 (18%) | ||
| HbSβ+thal | 6 (11%) | ||
| Other | 2 (4%) | ||
| Trait Status | N/A | N/A | |
| Unknown | 5 (9%) | ||
| No | 28 (49%) | ||
| Yes | 24 (42%) | ||
| S trait | 16 (28%) | ||
| C trait | 2 (4%) | ||
| Thal trait | 1 (2%) | ||
| Unknown | 5 (9%) | ||
| Hydroxyurea | 23 (42%) | N/A | |
| Yes | |||
| Number of Prior Pain Encounters | N/A | N/A | |
| Median (IQR) | 8 (3.5-23.5) | ||