LPS (1 mg/kg, IP) or PBS was injected into WT, hSR-BI and hSR-BII tgn mice. Six hours after the LPS injection, mice were euthanized for plasma and organ collection. Plasma levels of IL-6 (A), MIP-2 (B), CXCL1 (C) and IL-1β (D) were determined by ELISA. Values are the mean ± SD (n=5). ** P<0.01, *** p<0.005, vs WT LPS-treated levels.