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. 2016 May 4;11(5):e0154674. doi: 10.1371/journal.pone.0154674

Fig 9. The top-ranked upstream transcription factors (in centre) suggested by IPA® for the set of down-regulated genes (outer circle).

Fig 9

The top two-ranked cytokines, IFNA2 and IFNL1 are also included. Genes with >1.2 fold down-regulation are in green; those with >1.2-fold up-regulation are in red. Color intensity corresponds to the fold change. Genes corresponding to immediate downstream targets of IRFs are enlarged with blue borders and connections.