Fig 3. Testing the hippocampus dependence of recent and remote memories.

a-c: Comparison of freezing levels (post-CNO and post-Vehicle injection) in the (a) recent memory test, (b) remote 1 memory test, (c) remote 2 memory test, for control mice (n = 12, red) and hM₄Di mice (n = 12, blue, cyan). d-e: Freezing levels following CNO (filled bars) and Vehicle (unfilled bars) injections for the Recent, Remote 1 and Remote 2 memory test in (d) hM₄Di mice and (e) control mice. (* P<0.005, Signed rank test). For the Remote 1 and Remote 2 tests, the mean CNO freezing level (across two successive tests) is plotted).