PAS |
180 paired stimuli, interval of 5 s, interstimulus interval of 25 ms between electrical and magnetic stimulus |
90 paired stimuli, interval of 20 s, ISI 25 ms between electrical and magnetic stimulus |
132 paired stimuli, interval of 5 s, ISI 25 ms between electrical and magnetic stimulus |
132 paired stimuli, interval of 5 s, ISI 25 ms between electrical and magnetic stimulus |
132 paired stimuli, interval of 5 s, ISI 25 ms between electrical and magnetic stimulus |
132 paired stimuli, interval of 5 s, ISI 25 ms between electrical and magnetic stimulus |
132 paired stimuli, interval of 5 s, ISI 25 ms between electrical and magnetic stimulus |
TMS |
TMS adjusted to 1 mV unconditioned MEP amplitude.20 MEPs per condition. Post measurements at 0, 8 and 15 minutes post intervention. |
TMS 0.5–1.0 mV interval 10 s, 20 MEPs per condition. Post measurements at 0, 15, 30 (60 min for study C) post intervention. |
TMS 0.5–1.0 mV; 10 MEPs per condition; post measurements at 0, 15, 30 post intervention. |
TMS 0.5–1.0 mV; 10 MEPs per condition; post measurements at 0, 15, 30 post intervention. |
TMS 0.5–1.0 mV; 10 MEPs per condition; post measurements at 0, 15, 30 post intervention. |
TMS 0.5–1.0 mV; 10 MEPs per condition; post measurements at 0, 15, 30 post intervention. |
TMS 0.5–1.0 mV; 10 MEPs per condition; post measurements at 0, 15, 30 post intervention. |
E-Stim |
300% of perception threshold at median nerve |
300% perception threshold at ulnar nerve |
300% of perception threshold at median nerve |
300% perception threshold at median nerve (some participants did not tolerate stimulation at 300% perception threshold, there the stimulation intensity was adjusted individually (mean 273%), a visible twitch of the thumb was required) |
300% of perception threshold at median nerve |
300% of perception threshold at median nerve |
300% perception threshold at median nerve (some participants did not tolerate stimulation at 300% perception threshold, there the stimulation intensity was adjusted individually (mean 277%), a visible twitch of the thumb was required) |
Muscle |
APB (right Hand, only right handed subjects) |
ADM (dominant hand) |
APB (right Hand, only right handed subjects) |
APB (right Hand, only right handed subjects) |
APB (right Hand, only right handed subjects) |
APB (right Hand, only right handed subjects) |
APB (right Hand, only right handed subjects) |
Other |
Neuronavigation, Attention monitored by counting visual stimuli Experiment conducted in the afternoon. |
Experiment conducted between 10 AM and 3 PM Attention monitored by counting number of ulnar nerve stimulations |
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Experiment conducted between 9 AM and 6 PM Attention monitored by counting number of ulnar nerve stimulations |
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Experiment conducted between 9 AM and 6 PM Attention monitored by counting number of median nerve stimulations |
Experiment conducted between 9 AM and 5 PM Attention monitored by counting number of ulnar nerve stimulations |