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. 2016 May 4;11(5):e0154690. doi: 10.1371/journal.pone.0154690

Table 3. Levels of leukocytes, neutrophils and monocytes during the course of sepsis.

Leukocyte total cell count x10(9)/L Median (IQR) Neutrophil cell count x10(9)/L Median (IQR) Monocyte cell count x10(9)/L Median (IQR)
Days after admission Severe sepsis/Septic shock Non-Severe sepsis Severe sepsis/Septic shock Non-Severe sepsis Severe sepsis/Septic shock Non-Severe sepsis
1–2 16.6 (9.8–18.5) n = 20 10.0 (6.4–14.5) n = 40 16.6 (9.8–18.5) n = 20 7.6 (4.7–11.8) n = 40 * 0.8 (0.40–1.2) n = 20 0.8 (0.5–1.2) n = 40
3 14.5 (8.0–25.0) n = 11 7.2 (5.4–10.4) n = 21 * 11.0 (6.4–19.3) n = 10 4.4 (3.5–7.6) n = 21 * 0.7 (0.5–1.4) n = 11 0.9 (0.5–1.0) n = 21
7 13.2 (11.8–19.1) n = 19 9.0 (6.3–11.5) n = 38 * 10.0 (8.3–12.0) n = 18 6.2 (4.0–8.1) n = 37 * 1.0 (0.8–1.3) n = 19 0.8 (0.5–1.0) n = 38
14 9.7 (7.1–11.8) n = 19 7.6 (6.3–9.8) n = 39 7.5 (4.8–9.6) n = 19 4.7 (3.6–6.3) n = 38 * 0.8 (0.6–1.0) n = 19 0.6 (0.5–0.8) n = 39
28 8.8 (5.8–13.1) n = 11 6.9 (5.1–8.1) n = 19 4.6 (3.1–9.4) n = 11 4.0 (3.0–5.3) n = 19 0.7 (0.6–0.9) n = 11 0.6 (0.5–0.8) n = 19

* Significant mean difference between severe sepsis/septic shock and non-severe sepsis (p<0.05, Bonferroni adjusted).