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In response to an unknown signal ArlS either phosphorylates or dephosphorylates ArlR. When ArlR is phosphorylated it binds to the mgrA promoter, activating expression of mgrA. MgrA in turn represses ebh and other unknown targets. When either arlRS or mgrA is disrupted then ebh is de-repressed, and production of Ebh presumably blocks clumping.
