Table 2.
Compounds that enhance the binding of Aβ oligomers to EphB2
Compound | Aβ binding (% of control) |
---|---|
Domiphen bromide | 386.8 |
Dopamine hydrochloride | 262.8 |
Pentamidine isethionate | 238.6 |
Levodopa | 214.9 |
Fluvoxamine maleate | 206.6 |
Five compounds that increased the Aβ oligomer binding to EphB2 to more than 200% in the screening are listed. Values are mean (n = 2). The concentration of drugs was 100 μm.