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. 2016 May 4;11(5):e0154583. doi: 10.1371/journal.pone.0154583

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© 2016 Tobalina et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — Essential gene frequency for reconstructed context-specific networks of selected cancer cell lines using our algorithm with Schema 3 and Recon2 as the base network. The horizontal axis contains the ENTREZ Symbols of the obtained essential genes. The height of the bars indicates the fraction of samples in which the gene appears as essential. The height of the black line indicates the fraction of randomly reconstructed network in which the corresponding gene appears as essential.