Skip to main content
. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: Oral Oncol. 2014 Aug 21;50(11):1098–1103. doi: 10.1016/j.oraloncology.2014.08.001

Table 2.

Clinical Oral Mucositis Scores

Oral Mucositis Assessment Scale (OMAS)
Intention to Treat Analysis Per Protocol Analysis (period of study medication use only)
Celecoxib
n=20		 Placebo
n=20		 P value Celecoxib
n=20		 Placebo
n=20		 P value
Mean OMAS Score (range 0–5) (SD) .98
(.77)		 .97
(.86)		 .8402 .86
(.72)		 .93
(.86)		 .6742
  Mean OMAS Ulceration (range 0–3), (SD) .52
(.53)		 .50
(.53)		 .6682 .45
(.49)		 .47
(.52)		 .7632
  Mean OMAS Erythema (range 0–2) (SD) .46
(.28)		 .47
(.38)		 .8402 .42
(.27)		 .46
(.38)		 .5802
  Mean OMAS Score (0–5) immediately after 5000 centigray radiation (SD) 1.42
(.67)
n=19 		1.36
(.88)		 .8311 1.31
(.68)
n=16 		1.41
(.87)
n=19 		.7211
 Mean Peak OMAS Score (range 0–5) (SD) 1.71
(.59)		 1.70
(.95)		 .9821 1.65
(.58)		 1.69
(.95)		 .8771
World Health Organization (WHO) Oral Mucositis Scale
Intention to Treat Analysis Per Protocol Analysis (period of study medication use only)
Celecoxib
n=20		 Placebo
n=20		 P value Celecoxib
n=20		 Placebo
n=20		 P value
Mean WHO Score (range 0–4) (SD) 1.94
(1.40)		 1.85
(1.43)		 .6542 1.74
(1.35)		 1.80
(1.43)		 .8882
 WHO Score immediately after 5000 cGy radiation (SD) 2.47
(1.17)
n=19 		2.55
(1.00)		 .8281 2.31
(1.20)
n=16 		2.58
(1.02)
n=19 		.4812
 Peak WHO Score (SD) 3.40
(.68)		 2.95
(1.15)		 .1391 3.05
(.76)		 2.95
(1.15)		 .7471
 Number of Days with WHO Grade 3 or 4 Mucositis (SD) 15.85
(13.48)		 17.05
(15.16)		 .7931 10.05
(10.79)		 13.85
(12.76)		 .3161
National Cancer Institute Common Toxicity Criteria (NCI-CTC) Oral Mucositis Scale
Intention to Treat Analysis Per Protocol Analysis (period of study medication use only)
Celecoxib n=20 Placebo n=20 P value Celecoxib n=20 Placebo n=20 P value
Mean NCI-CTC Score (Range 0–4) (SD) 2.00
(1.07)		 1.85
(1.12)		 .3242 1.86
(1.07)		 1.81
(1.13)		 .6542
 NCI-CTC immediately after 5000 cGy Radiation (SD) 2.63
(.60)
n=19 		2.50
(.83)		 .5741 2.56
(.63)
n=16 		2.53
(.84)
n=19 		.8881
 Peak NCI-CTC (SD) 2.85
(.37)		 2.55
(.37)		 .0931 2.84
(.38)		 2.55
(.69)		 .1101
 Number of Days with NCI- 19.60 18.20 .7671 14.35 16.15 .6671
 CTC Grade 3 or higher (SD) (14.12) (15.50) (12.27) (13.96)
1

Two-sample t-test,

2

linear mixed models