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. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: Cell. 2015 Jan 15;160(1-2):48–61. doi: 10.1016/j.cell.2014.12.033

Figure 4. Endogenous retroviruses tied to local immunity.

Figure 4

(A) RNA-Seq-derived ERV expression in reads per million (RPM) across 18 TCGA tumor types and 27 non-tumor tissue types (from TCGA and GTEX) for three elements found to be tumor-specific. The expression ranges (minimum value to maximum value) are highlighted in orange (for tumor tissues) or green (for non-tumor tissues). (B) Spearman-rank correlations between CYT and ERV expression. Gray squares indicate non-significant association (unadjusted p>0.05) and blank squares indicate no over-expression of the given ERV in the given tumor type (expression strictly below the normal tissue maximum). Asterisks (*) denote Bonferroni-significant associations (adj. p<0.05). See also Data S4 and Table S5.