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. Author manuscript; available in PMC: 2016 May 4.
Published in final edited form as: JAMA Neurol. 2015 Apr;72(4):396–404. doi: 10.1001/jamaneurol.2014.4103

Table 2.

Heritability estimates based on the discovery cohort of myasthenia gravis

All SNPs
Significant loci only
Heritability

estimate		 95% CI P Heritability

estimate		 95% CI P
All cases 25.6% 18.6 – 32.6 8.79×10−14 1.8% 0.8 – 2.7 5.42×10−9
Early-onset cases 37.9% 16.8 – 59.0 5.61×10−5 2.8% 0.7 – 4.9 1.55×10−7
Late-onset cases 35.3% 27.1 – 43.5 <1.00×10−20 2.1% 0.9 – 3.2   1.73×10−13

95% CI, 95% confidence interval.