Fig. 2.

Fbxo30 deficiency affects luminal vs basal lineage choice. a. Representative FACS profiles depicting selective reduction in luminal epithelial cells in the mammary gland of the Fbxo30^−/− mice. The markers and gating strategy used to define specific mammary gland cell types are indicated. b. Reduction in luminal/basal ratio among Fbxo30^−/− mammary epithelial cells. c. Number of recoverable luminal and basal epithelial cells in mammary gland per mice. Data shown are number of epithelial cells with either luminal or basal epithelial cell markers based on FACS staining. Data shown in this figure are representative data from an experiment involving 3 mice in each group and have been reproduced three times.