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. Author manuscript; available in PMC: 2017 May 3.
Published in final edited form as: Circulation. 2016 Apr 4;133(18):1783–1794. doi: 10.1161/CIRCULATIONAHA.115.020617

Figure 3.

Figure 3

BMPR2 silencing in control PAECs induces increased HMGA1 and EndMT markers. Commercially available PAECs were transfected with siRNA for BMPR2 (B2) or control non-targeting siRNA (Con). (A) Gene expression changes were assessed by qPCR after 72h. (B) Representative immunoblot and densitometric quantification of protein expression assessed 7 days after siRNA transfection. Snail/Slug indicates an antibody recognizing both Snail and Slug proteins. (C) Representative immunoblot and densitometric quantification of protein expression assessed 7 days after siRNA transfection. Boxplots indicate minimum, maximum and median for n=9 (A and B). Scatterplots indicate mean±SEM for n=3 (C). *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001 compared to respective Con by Student’s t-test.