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. 2016 May 4;94(5):1065–1072. doi: 10.4269/ajtmh.15-0280

Table 3.

Total cost to the health system and households between 2010 and 2012 and cost of loss of income due to premature death (with no correction for underreporting)

Type of cost Cost (US$) (95% CI*)
2010 2011 2012
Cost to health system
 Outpatient DF 5,650,192 (5,586,556–5,713,360) 1,804,802 (1,753,591–1,851,990) 1,569,644 (1,438,477–1,703,801)
 Hospitalized DF 8,585,571 (8,013,977–9,145,049) 4,601,103 (3,912,993–5,104,008) 5,160,365 (4,320,472–5,810,157)
 DHF 14,736,394 (8,939,089–24,885,807) 2,412,136 (1,983,166–2,789,072) 2,907,075 (2,076,198–3,898,951)
 Total 28,972,157 (22,539,621–39,744,215) 8,818,041 (7,649,750–9,745,069) 9,637,084 (7,835,147–11,412,910)
Cost to household
 Direct medical costs
  Outpatient DF 1,421,718 (1,176,112–1,692,248) 257,279 (212,833–306,235) 439,126 (363,265–522,684)
  Hospitalized DF 1,268,639 (1,101,221–1,468,579) 417,141 (362,092–482,883) 791,732 (687,250–916,510)
  DHF 558,397 (442,114–715,721) 74,663 (59,115–95,699) 83,946 (66,465–107,597)
  Total 3,248,754 (2,719,447–3,876,548) 749,084 (634,041–884,818) 1,314,804 (1,116,980–1,546,791)
 Direct non-medical costs§
  Outpatient DF 3,177,839 (2,903,072–4,466,444) 575,073 (525,350–627,300) 981,538 (896,671–1,070,679)
  Hospitalized DF 1,698,782 (1,569,223–1,836,728) 558,576 (515,976–603,935) 1,060,175 (979,320–1,146,265)
  DHF 610,148 (540,237–686,268) 81,583 (72,235–91,761) 91,726 (81,216–103,169)
  Total 5,486,769 (5,012,532–5,989,440) 1,215,232 (1,113,561–1,322,995) 2,133,439 (1,957,207–2,320,113)
 Indirect costs
  Loss of productivity (patient) 4,667,680 (3,669,908–5,821,233) 1,003,138 (778,103–1,266,680) 1,762,657 (1,364,210–2,230,539)
  Loss of productivity (caregiver) 3,462,388 (2,839,031–4,192,188) 743,476 (614,549–893,959) 1,284,073 (1,063,016–1,542,116)
  Total 8,130,068 (6,508,939–10,013,421) 1,746,614 (1,392,651–2,160,639) 3,046,730 (2,427,227–3,772,655)
Loss of income due to premature death 17,680,602 2,847,140 2,908,688
Total costs 63,518,350 (54,461,141–77,304,226) 15,376,111 (13,637,144–16,960,661) 19,040,745 (16,245,249–21,961,157)

CI = confidence interval; DF = dengue fever; DHF = dengue hemorrhagic fever.

Costs are derived from the survey of Centro de Estudios sobre Desarrollo Económico, prepared from Ministry of Health and Social Protection and survey of households, Registro Individual de Prestación de Servicios de Salud (RIPS; 2010–2012), RIPS sample of towns (2010–2012), and Sistema Nacional de Vigilancia en Salud Pública (2010–2012) and are based on cost per case analysis presented by Castro and others.11

*

Calculated using a bootstrap method (see text for details).

Includes medical appointments, treatments, and other services.

Co-payment and medicines.

§

Transport, nurses' and carers' fees, lodging, food, child carers' fees, changes to living quarters, post-disease expenses, and other expenses.