. Author manuscript; available in PMC: 2017 May 1.

Published in final edited form as: Bioorg Med Chem Lett. 2016 Mar 18;26(9):2188–2193. doi: 10.1016/j.bmcl.2016.03.066

Table 3.

Minimum bactericidal concentration and Low Oxygen Recovery Assay results.

Code	MIC H₃₇RV		MBC		LORA
Code	μg/mL	% Inh^a	μg/mL	MBC/MICH₃₇RV	μg/mL	MIC H₃₇RV/LORA
3	2	80	NA	-	UR	-
16	2	61	TNTC	-	0.25	8
18	1	78	NA	-	>8	Nd
21	1.5	78	4	2.6	0.375	4
24	0.75	51	NA	-	>12	Nd
RIF	0.05	55	0.78	15.6	0.39	-

Percentage inhibition at the MIC concentration.

UR: Unreportable: Compound precipitated out of solution. NA: Not applicable: colony counts above the established rejection value ≥ 40. TNTC: Too numerous to count. Nd: Not determinated.