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. 2016 Jun 1;95(2):772–781. doi: 10.1016/j.ijrobp.2016.01.035

Fig. 1.

Fig. 1

Olaparib radiosensitizes NSCLC cell lines in vitro. Calu-6 and Calu-3 cells were exposed to normoxia (21% O2) or hypoxia (1% O2). Olaparib or vehicle was added to the medium 1 hour before radiation. At 24 hours after radiation, cells were cultured in drug-free medium for clonogenic survival assays. (A) Clonogenic survival curves under normoxia. (B) Clonogenic survival curves under hypoxia. Abbreviation: SER = sensitization enhancement ratio.