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Combination of radiation with olaparib induces significant growth inhibition in Calu-6 xenografts but not in Calu-3 xenografts. Tumor-bearing mice were randomized (n=6/group) to receive vehicle, olaparib (50 mg/kg), 10-Gy radiation, or olaparib combined with radiation. The growth curves of Calu-6 xenografts (A) and Calu-3 xenografts (B) were plotted (mean ± SEM). ***P<.001. n=3/group. Abbreviation: ns = not significant.
