Figure 6.

The CLE peptide receptors likely share a conserved ligand recognition mechanism. (A) Superposition of the crystal structure of PXY-TDIF with modeled structures of other known CLE receptors. (B) Superposition of the key TDIF-interacting residues of PXY with their equivalents from the modeled structures. These interacting residues are shown in stick. (C) Frequency plots of the TDIF-interacting residues among the known CLE receptors. V3, Hyp4, G6, N8, and N12 are the conserved residues among the CLE peptides (numbering based on TDIF). Numbers at the bottom indicate the positions of the conserved residues in PXY.