Table 3.
Univariate and Multivariate Cox Proportional Hazards Regression Analysis of MVI in Relation to miR-125b and Clinical Parameters of 108 HCC Patients
| Variable | Logistic |
|||
|---|---|---|---|---|
| Univariate Analysis |
Multivariate Analysis |
|||
| HR (95%CI) | P Value | HR (95%CI) | P Value | |
| miR-125b | 0.409 (0.263-0.635) | .000 | 0.371 (0.211-0.654) | .001 |
| Tumor size | 1.449 (1.193-1.761) | .000 | 1.522 (1.181-1.960) | .001 |
| AFP | 1.301 (1.121-1.510) | .001 | 1.348 (1.104-1.645) | .003 |
| Envelope invasion | 4.568 (1.688-12.356) | .003 | ||
| BCLC | 4.143 (1.725-9.949) | .001 | ||
| Differentiation | 1.743 (0.778-3.902) | .177 | ||
| GGT | 1.181 (0.670-2.081) | .566 | ||
| Hepatitis | 1.216 (0.313-4.717) | .778 | ||
| Cirrhosis | 1.012 (0.325-3.154) | .983 | ||
| Tumor multiplicity | 0.879 (0.218-3.553) | .857 | ||
| Gender | 0.894 (0.307-2.606) | .838 | ||
| Age | 1.002 (0.966-1.039) | .923 | ||