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. 2016 Mar 2;41(8):2171–2177. doi: 10.1038/npp.2016.18

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Copyright © 2016 American College of Neuropsychopharmacology

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Whole-brain seed-correlation comparing right inferior frontal gyrus (IFG) connectivity between placebo and atomoxetine sessions in patients with Parkinson's disease. (a) Right IFG seed region centered on 56, 16, and 12 (in blue). (b) Voxel-wise correlation map showing increased connectivity after atomoxetine in patients, between right IFG and bilateral dorsal anterior cingulate (in orange) (atomoxetine>placebo; peak p<0.05 family-wise error (FWE)-corrected, z=4.73). (c) Scatter plot showing the functional connectivity between right IFG and dorsal anterior cingulate peak during placebo and atomoxetine sessions for each patient. ACC, anterior cingulate cortex.