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. 2016 Mar 14;44(8):3958–3968. doi: 10.1093/nar/gkw145

Figure 1.

Figure 1.

A folding topology of a Tel23 G4 induced by BMVC-8C3O. (A) Imino proton NMR spectra of the Tel23 G4 in the presence of 150 mM K+ (bottom) and time-resolved imino proton NMR spectra recorded at 10 min and at 0.5, 2, 5 and 10 h after addition of 5 eq. BMVC-8C3O at 310 K, as indicated in the ascending order. (B) An expanded NOESY spectrum of the Tel23 G4 in complex with BMVC-8C3O; the spectrum was recorded with mixing time 250 ms and showed the H1/H8 correlations. Green, black and red labels correspond to the top, middle and bottom G-quartets, respectively. (C) Schematic representation of the Tel23 G4 topology induced by BMVC-8C3O.