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. 2016 Apr 22;6(3):189–197. doi: 10.1016/j.apsb.2016.03.009

Figure 4.

Fig. 4

Parishin C had no effects on normal LTP and ion channels. (A) Upper traces of PS before (1) and after (2) HFS in two groups. Parishin C 20 mg/kg given i.p. 30 min before HFS did not influence the baseline and LTP induction in normal rats (control group n=8, pC group n=7). (B) Perfusion of 10 μmol/L parishin C for 10 min had no effects on AMPAR currents in primary cultured hippocampal pyramidal neurons. The bars above current recordings show pressure injection of 1 s, 3 μmol/L AMPA (n=3). (C) Perfusion of 10 μmol/L parishin C for 10 min had no effects on NMDAR currents in primary cultured hippocampal pyramidal neurons. The bars above current recordings show pressure injection of 1 s, 100 μmol/L NMDA and 10 μmol/L glycine (n=5). Data were shown in mean±SEM. The amplitudes of all currents were normalized to the first evoked at –70 mV.