Table 2. Top 20 corona proteins identified after incubating with plasma for 3 h.
No. | AgNP-CIT-20F |
AgNP-CIT-20M |
AgNP-PVP-20F |
AgNP-PVP-20M |
||||
---|---|---|---|---|---|---|---|---|
Protein(gene) | Abundance* | Protein(gene) | Abundance* | Protein(gene) | Abundance* | Protein(gene) | Abundance* | |
1 | Kininogen-1 (KNG1) | 35.42165 | Kininogen-1 (KNG1) | 35.57028333 | Kininogen-1 (KNG1) | 35.43163333 | Kininogen-1 (KNG1) | 35.25791667 |
2 | Fibrinogen alpha chain (FGA) | 33.46088334 | Apolipoprotein E (APOE) | 33.55425 | Apolipoprotein A-I (APOA1) | 33.09685 | Apolipoprotein E (APOE) | 33.43363334 |
3 | Apolipoprotein A-I (APOA1) | 33.00553334 | Fibrinogen alpha chain (FGA) | 33.23846667 | Vitronectin (VTN) | 33.09233334 | Fibrinogen alpha chain (FGA) | 32.95638334 |
4 | Vitronectin (VTN) | 32.81335 | Apolipoprotein A-I (APOA1) | 33.12035 | Apolipoprotein E (APOE) | 32.71623334 | Vitronectin (VTN) | 32.7894 |
5 | Apolipoprotein E (APOE) | 32.80266667 | Vitronectin (VTN) | 32.71365 | Fibrinogen alpha chain (FGA) | 32.6453 | Apolipoprotein A-I (APOA1) | 32.60831667 |
6 | Fibrinogen beta chain (FGB) | 32.36591667 | Fibrinogen gamma chain (FGG) | 32.19898334 | Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4) | 32.06611667 | Plasma kallikrein (KLKB1) | 31.95661667 |
7 | Fibrinogen gamma chain (FGG) | 32.30948334 | Fibrinogen beta chain (FGB) | 32.17975 | Fibrinogen gamma chain (FGG) | 31.78608333 | Coagulation factor V (F5) | 31.73656667 |
8 | Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4) | 31.84591667 | Coagulation factor V (F5) | 31.79088334 | Coagulation factor V (F5) | 31.4815 | Fibrinogen gamma chain (FGG) | 31.70983334 |
9 | Coagulation factor V (F5) | 31.69698333 | Plasma kallikrein (KLKB1) | 31.64233333 | Fibrinogen beta chain (FGB) | 31.29676667 | Fibrinogen beta chain (FGB) | 31.59158334 |
10 | Complement C4-B (C4B) | 31.10568334 | Inter-alpha-trypsin inhibitor heavy chain H4(ITIH4) | 31.1836 | Plasma kallikrein (KLKB1) | 30.7676 | Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4) | 31.2543 |
11 | Plasma kallikrein (KLKB1) | 31.05406667 | Complement C4-B(C4B) | 30.88695 | Ig gamma-1 chain C region (IGHG1) | 30.66883334 | Complement C4-B (C4B) | 31.11485 |
12 | Complement C3 (C3) | 30.40113333 | Coagulation factor XI(F11) | 30.71216667 | Complement C3 (C3) | 30.58146667 | Complement C3 (C3) | 30.61288334 |
13 | Coagulation factor XI (F11) | 30.27568334 | Complement C3(C3) | 30.61853334 | Complement C4-B (C4B) | 30.01456667 | Serum albumin (ALB) | 30.45698334 |
14 | Ig gamma-1 chain C region (IGHG1) | 29.76771667 | Ig gamma-1 chain C region(IGHG1) | 30.25201667 | Coagulation factor XI (F11) | 29.82581667 | Ig gamma-1 chain C region (IGHG1) | 30.44638334 |
15 | Serum albumin (ALB) | 29.64955 | Serum albumin(ALB) | 29.70115 | Serum albumin (ALB) | 29.39855 | Coagulation factor XI (F11) | 30.38823334 |
16 | Platelet factor 4 (PF4) | 29.5006 | Apolipoprotein C-II (APOC2) | 29.44895 | Apolipoprotein C-II (APOC2) | 29.33451667 | Proteoglycan 4 (PRG4) | 29.84238334 |
17 | Apolipoprotein C-II (APOC2) | 29.30501667 | Ig kappa chain C region (IGKC) | 29.35978334 | Apolipoprotein A-IV (APOA4) | 29.31788334 | Apolipoprotein C-II (APOC2) | 29.7589 |
18 | Apolipoprotein A-IV (APOA4) | 29.1102 | Proteoglycan 4 (PRG4) | 29.27093334 | Proteoglycan 4 (PRG4) | 29.2332 | Plasma serine protease inhibitor (SERPINA5) | 29.48916667 |
19 | Ig kappa chain C region (IGKC) | 28.98816667 | Apolipoprotein C-I (APOC1) | 29.11438334 | Plasma protease C1 inhibitor (SERPING1) | 29.203 | Ig kappa chain C region (IGKC) | 29.47166667 |
20 | Apolipoprotein C-I (APOC1) | 28.983 | Platelet factor 4 (PF4) | 28.99733334 | Ig kappa chain C region (IGKC) | 29.03638334 | Plasma protease C1 inhibitor (SERPING1) | 29.26511667 |
*Represent the log2 (Av.intensity) of protein identified with LFQ.