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. 2016 May 5;6:25564. doi: 10.1038/srep25564

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Copyright © 2016, Macmillan Publishers Limited

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In EPM test sleep deprived animals spent more time in closed arm (A) however TSD animals spent more time in exploration as indicated by higher number of entries and crossings (B,C). TSD group showed suppressed anxiety-like behavior and had higher number of head dips as compared to VSD (D). In NOR test TSD animals showed almost similar behavior as VUD animals as indicated by higher number of episodes for each object as compared to VSD animals (E). TSD group spent more time in exploring each object as compared to VSD animals (F,G). However there is not much difference in preference index for each object among the three groups (H). ‘*’ represent statistical significant difference p < 0.05 as compared to VUD group, ‘#’ represent statistical significant difference p < 0.05 as compared to VSD animals and ‘§’ represent statistical significant difference within the group.