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. 2016 May 5;6:25492. doi: 10.1038/srep25492

Figure 3. Long-term effect of Bufei Yishen formula (BYF) on the expression of IL-1β, IL-6 TNF-α and sTNFR2, in the lung of chronic obstructive pulmonary disease (COPD) rats.

Figure 3

COPD rats were intragastricly treated with BYF (4.44 g/kg) and aminophylline (APL, 2.3 mg/kg) once daily from week 9 to 20. On week 32, the expression of interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, and soluble TNF-α receptor (sTNFR) 2 in lung tissues were evaluated by immunohistochemistry (magnification, ×100) (A). Quantitative analysis for the expression of IL-6, IL-10, TNF-α, and sTNFR2 in the lung of COPD rats (B). Values represent the means ± SEM. **p < 0.01 vs. model.