Skip to main content
. 2016 May 5;6:25492. doi: 10.1038/srep25492

Figure 5. Long-term effect of Bufei Yishen formula (BYF) on the expression of collagens I, III and IV in the lung tissues of chronic obstructive pulmonary disease (COPD) rats.

Figure 5

COPD rats were intragastricly treated with BYF (4.44 g/kg) and aminophylline (APL, 2.3 mg/kg) once daily from week 9 to 20. Immunohistochemical analysis for the expression of collagens I, III, and IV in the lung of COPD rats on week 32 (original magnification ×100) (A). Quantitative analysis for the expression of collagens I, III, and IV in the lung tissues (B). Data are presented as means ± SEM. *p < 0.05, **p < 0.01 vs. model.